故事发生在位于婆罗洲的原始丛林中,比尔(约翰尼·梅辛纳 Johnny Messner 饰)带领着他的探险小队穿行于其中,寻找着一种名为“血兰”的珍稀植物。在记载中,血兰拥有着能够使人长生不老的神秘力量,“几乎从未有人获得过它”的传闻也令血兰逐渐成为了传说。这一次,受一家著名的医药公司所托,比尔一行人决定揭开血兰的神秘面纱。 在离目标越来越近的同时,危险也不期而至。血兰的力量没有使人类返老还童,却将一群蛇类变得凶猛而恐怖,为了挪动巨大的身体,它们不得不吃下比以往多达数倍的食物,而此时冒昧来访的人类,成为了它们最好的猎物。一边是丛林中恶劣的生态环境,一边是穷凶极恶的食人恶兽,同伴们一个接着一个的悲惨死去,比尔最终能够自保,并且挽救更多的生命吗?In New York, the ambitious Dr. Jack Byron and his associate Gordon Mitchell present the research of his assistant Sam Rogers to the CEO and board of directors of a corporation to sponsor a scientific expedition to Borneo. The objective is to find a flower, Blood Orchid, that flourishes for a couple of weeks every seven years and could be a fountain of youth, prolonging the expectation of life of human beings. They are succeeded and once in Borneo, they realize that it is the raining season and there is no boat available to navigate on the river. They pay US$ 50,000.00 to convince Captain Bill Johnson and his partner Tran to sail to the location. After an accident in a waterfall, the survivors realize that a pack of anacondas have gathered for mating and their nest is nearby the plantation of Blood Orchid, which made them bigger and bigger.