原本对生活怀有极大热情的结衣(佐佐木希 饰),在遭遇了佐伯俊雄一家后命运彻底发生转变,她的身影消失在那栋阴森可怖的房子里,而关于复仇的故事却仍未结束。结衣的姐姐麻衣(平爱梨 饰)做了一个关于妹妹的不祥之梦,事后她想方设法联系结衣,然而始终没有回音。俊雄在遭遇了父亲刚雄(绯田康人 饰)屠杀母亲伽椰子的血腥惨剧后,她被亲戚接走,和姐姐玲央(小野乃乃香 饰)一家住在一起。从这天开始,玲央家怪事不断,住在对面医院的小女孩更目睹到俊雄可怕的一面。 伽椰子的怨念愈演愈烈,无差别的复仇波及到了每一个和佐伯家扯上关系的陌生人……Following the events of Ju-on: The Beginning of the End, Mai, the older sister of elementary schoolteacher Yui Shono, goes to look for her sister, who disappeared after a year while working in an elementary school. Mai soon discovers the Teriyaki household who tells her about what happened to her sister. Mai will now uncover the dark secrets of Ju-on and will try to end the curse once and for all.